Efficacy of repetitive transcranial magnetic stimulation for subjective chronic tinnitus: a randomized controlled trial meta-analysis
Elevated glutamatergic activity is thought to contribute to both acute tinnitus originating in the cochlea and chronic tinnitus arising from maladaptive changes within the central auditory pathway
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The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)
It has also been indicated that riboflavin deficiency decreases the mRNA level of antioxidant enzymes in muscle (GR, GPx, SOD and CAT) (Reference Jiang, Chen and Liu33) , intestine (GR, GPx and SOD) (Reference Chen, Feng and Jiang34) and gills (GR, SOD) (Reference Chen, Feng and Jiang35) of fish
