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But they work in totally different ways: Sermorelin therapy: stimulates the pituitary gland to release growth hormone, which increases IGF-1 and supports bone, muscle, and metabolic function Estrogen therapy: binds to estrogen receptors rather than growth hormone receptors, impacting many of the same tissues, including bones, muscles, and fat As women balance the symptoms that arise during perimenopause and midlife, finding the right solution varies based on personal needs, body type, and other health factors

CK and ED reviewed and made significant contributions to the manuscript

Hydrated cells = better fat metabolism and appetite regulation Your gut bacteria help regulate: Eat more : A healthy gut can help you lose weight naturally

Exercising regularly, focusing on gradual weight loss, and wearing supportive footwear can help protect your skin and support your comfort as your body changes

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