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955 Yu et al

Although VIP is mainly secreted by nervous tissue, it is also produced by several immune cells, such as eosinophils, mast cells and lymphocytes [84,85,86]

The NADPH system is also responsible for generating free radicals in immune cells by NADPH oxidase

The process of the removal of old erythrocytes from the circulation is also known as senescence, and similar to eryptosis, this process may be preferentially executed due to oxidative stress, hyperosmolarity, and energy depletion [24, 134]

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