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Watch closely for new or worsening depression, suicidal thoughts, or unusual changes in behavior

In such cases, Zepbound should be discontinued immediately, as these conditions represent absolute contraindications to continued use

At least 6 days of recovery time was introduced between pharmacological treatments to eliminate possible residual effects from the previous treatment and to enable monitoring food intake on subsequent days (Thursdays and Fridays)

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The study covered data on 28 million people with commercial insurance