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Progression through various disease stages in cirrhosis is fraught with complications related to portal hypertension and chronic liver failure, such as acute variceal bleeding, ascites, hydrothorax, hepatic encephalopathy (HE), life-threatening infections, and extrahepatic organ failure, such as hepatorenal syndrome and additionally, hepatocellular carcinoma (2)

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In contrast, colorectal cancer (CRC) is characterized by decreased OCTN2 expression (Juraszek and Nalecz, 2019)

Although treatment is associated with short-term side effects, such as decreased appetite [46], weight loss, headaches, anxiety [13,46], and sleep problems [47], it also has long-term effects, such as impacting bone health [46,48]

~ AlphaMD Testosterone replacement therapy is a common treatment for men with low testosterone levels