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Perkins BA, et al

McNeill DR, Narayana A, Wong HK, Wilson DM

Warning signs include persistent fatigue despite adequate sleep, cold intolerance (especially cold hands and feet), menstrual irregularity or cessation in female subjects, hair thinning or shedding, and mood disturbances (irritability, low motivation)

En estudios preclnicos se han documentado efectos cardioprotectores mediados por el receptor ghrelinrgico cardaco directo (mejora de funcin ventricular en isquemia-reperfusin y modelos de insuficiencia cardaca)

Primary outcomes, energy expenditure and substrate utilization, were measured before and for 6 h after ingestion of the liquid test meal, using a ventilated hood system (Omnical, Maastricht University, The Netherlands) 47