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These modulatory effect of activated GLP-1R in the brain might be playing a crucial role which ultimately leads to neuronal cell survival, synaptic function, and improve in neuroinflammation in case neurodegenerative diseases

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Supernatants were subsequently acidified with 0.5% trifluoroacetic acid (TFA), followed by desalting using reversed-phase spin tips (Glygen Corp) and drying using vacuum centrifugation