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Direct answer: Semaglutide is generally safe long-term, but patients should expect ongoing digestive effects and require routine monitoring

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Four (4) events of hypoglycemia defined as a plasma glucose less than 54 mg/dL occurred in 2 (1.6%) of 125 SAXENDA-treated patients and 1 event occurred in 1 (0.8%) of 126 placebo-treated patients