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The upper body is not affected (except for arms in some types), so the size of the lower body is disproportionate and the body shape is distorted

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The FDA prescribing information notes that tirzepatide delays gastric emptying and has the potential to impact the absorption of oral medications, including those with narrow therapeutic indices like levothyroxine

Neurovascular pathways to neurodegeneration in Alzheimers disease and other disorders