step 4 semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial Semaglutide (Wegovy) for the Treatment

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Acknowledgments Authors want to thank Germaine Pugh and Cassia McClain for their invaluable help in preparing the manuscript, and Jessica Michelle Vasquez-Soltero for processing the gene profiling data