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On the other hand, pathophysiological features exhibited the association between mitochondrial dysfunction, decreased activity of complex I and complex IV of the electron transport chain, and the glutathione system in MS [23]

Pretreatment of mice with either grape seed extract (100 mg/kg/day for 7 days) or green tea extract (0.25% - 1% of diet for 5 days) protected livers from acetaminophen-mediated damage, as determined by serum levels of ALT and microscopic examination (Bagchi 2002