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Moreover, T1D follows a seasonal variation pattern where new diagnoses in children peak in autumn and winter months and trough in summer months in both the northern and southern hemispheres (132, 133)

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This lack of delay would represent a major advantage if translatable to humans, given that conventional antidepressants typically require 2-6 weeks before patients experience relief

It is a synthetic peptide derived from Body Protection Compound, a protein found in gastric juice

The approach differs significantly between deficiency with and without neurological involvement