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Description

Biochemistry, Lipase

Extrathyroidal manifestations, including GO, pretibial myxedema, and acropachy, can be observed to various extents (1317)

Researchers believe this may be connected to glutathione's role in the body's natural detoxification pathways

and Edward DAlessandro, Jr

We observed no significant inhibition of UGT1A1 or other transporters for SEP-479 and no hyperbilirubinemia in any of the non-clinical studies to date for SEP-479, including the 7-day and 28-day GLP toxicology studies in healthy cynomolgus monkeys