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GLP-1 use and hospital admissions were obtained from medical records

CFZ is highly lipophilic and is characterized by an unusually long pharmacokinetic half-life of up to 70 days, which is associated with extensive accumulation of the drug in the body [110,111,112]

The main analysis evaluated the association between GLP-1RA prescriptions and AUDIT-C scores

It adds that baseline nausea, reflux or inflammatory bowel conditions amplify gastrointestinal risk, and that interactions with certain diabetes agents or gastroprokinetic drugs also matter

Deficiency of mitochondrial glycerol 3-phosphate dehydrogenase exacerbates podocyte injury and the progression of diabetic kidney disease