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It is hypothesized that ferroptosis may be closely associated with arachidonic acid metabolism and the inflammatory response

From roughly weeks two through six (the proliferative phase), fibroblasts deposit new collagen

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In parallel, causal in vivo studies targeting key structural regulators of these contact sites, such as MFN2 and other tethering proteins, will be particularly informative for determining whether disruption of organelle interaction hubs directly contributes to mitochondrial dysfunction, metabolic imbalance, and functional ovarian decline

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