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10.1038/s41586-019-1170-y 156 WangX.XuZ.RenX.ChenX.YiQ.ZengS.et al (2022b)

Thats changed

This study below, published in 1967 carried out trials to determine how long cyanocobalamin and hydroxocobalamin B12 injections lasted before excretion in urine but you can see from their summary that it would be unreliable to assume that one size fits all

175-181 The finding that the administration of all-trans retinoic acid (ATRA) in elastase-induced emphysema in rats reversed the emphysematous changes, 182 suggested that ATRA might be a beneficial therapy for patients with emphysema