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59 Small molecule GLP-1RA in preclinical trials MLX-7005 MLX-7005 is a highly potent, oral small-molecule GLP-1 receptor agonist (GLP-1RA) that robustly activates the GLP-1 receptor cAMP signaling pathway without measurable -arrestin recruitment

doi: 10.1007/s13197-019-04041-9 127 MistryRHLiuFBorewiczKLohuisMAMSmidtHVerkadeHJet al

Change in albuminuria and GFR as end points for clinical trials in early stages of CKD: a scientific workshop sponsored by the National Kidney Foundation in collaboration with the US Food and Drug Administration and European Medicines Agency

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