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Another trial, centered around 405 patients, should conclude in December 2025

2.3.3 Extra-endocrine expression of taste receptors Beyond EECs, it is also important to mention that taste receptors may also be present in the brush cells, a subgroup of solitary chemosensory cells found in the nasal cavity and other regions of the gut, especially where food passes from the fundus to the corpus, and digestive process are initiated, where expression of TAS1R1, TAS1R3, and a-gustducin are involved, suggesting a role in amino acid sensing (60, 78, 79)

However, individual needs vary based on baseline status, dietary intake, and concurrent medications

TL;DR GLP-1 drugs such as semaglutide, tirzepatide, and liraglutide can help reduce appetite and body weight, but emerging research shows they may also increase the risk of protein, vitamin, and mineral deficiencies, especially when appetite drops sharply and food intake becomes too low or too limited

Commercial electrolyte products work well for convenience